Graduate Courses for Bioengineering (BIOE)
Schedule of Classes:
Fall |
Winter |
Spring |
Summer
(Only current and next semester available)
BIOE 404 Biomechanics (3 credits)
Prerequisite: BIOE120 and BIOE121. For BIOE majors only.
Introduction to the fundamentals of biomechanics including force
analysis, mechanics of deformable bodies, stress and strain, multiaxial
deformations, stress analysis, and viscoelasticity. Biomechanics of
soft and hard tissues.
BIOE 411 Tissue Engineering (3 credits)
Prerequisite: at least one biology course and MATH241. Recommended:
BSCI330 and BIOE340.
A review of the fundamental principles involved in the design of
engineered tissues and organs. Both biological and engineering
fundamentals will be considered.
BIOE 415 Bioengineering of Exercise Response (3 credits)
Prerequisite: MATH246 or permission of department. Credit will be
granted for only one of the following: BIOE415 or ENBE415. Formerly
ENBE415.
Exercise physiology in quantitative terms. Modeling and prediction of
cardiovascular, respiratory, thermoregulatory, biomechanical, and
metabolic aspects of human exercise responses.
BIOE 420 Bioimaging (3 credits)
Prerequisite: BIOE120, BIOE121, and MATH246. For BIOE majors only.
Examines the physical principles behind major biomedical imaging
modalities and new ways of using images for bio-related applications.
BIOE 422 Biosystems Engineering (3 credits)
Prerequisite: BIOE120 and BIOE121 or BSCI105; and one of the following
courses: BIOE331, BIOE332, ENCE305, or ENME331.
Conservation of mass in the context of biological systems at different
scales (i.e., cellular, organ, and ecosystem), life cycles such as
carbon cycle, nitrogen cycle, photosynthesis, water cycle, Kreb cycle,
and aerobic and anaerobic cycles as they relate to biosystem function
and health.
BIOE 425 Mechanical Properties of Biological Tissues (3 credits)
Prerequisite: ENES220 and MATH241. For BIOE majors with senior or
graduate standing only.
An exploration of mechanical properties of living biological tissues;
including hard and soft tissues. Coverage will include all the
traditional mechanical properties applied to biological tissues,
including: stress-strain behavior, elastic, viscoelastic,
thermomechanical, fracture, fatigue, etc. Additionally, alteration of
mechanical properties of living tissues due to disease, development,
growth, and remodeling will be covered.
BIOE 450 Quantitative Cell Physiology (3 credits)
One hour of lecture and two hours of discussion/recitation per week.
Recommended: MATH141, MATH241, MATH246 or equivalent.
Introduction to quantitative aspects of enuronal, skeletal muscle and
cardiac physiological systems, with an emphasis on cellular function
and plasticity.
BIOE 453 Biomaterials (3 credits)
Credit will be granted for only one of the following: ENBE453, BIOE453
or ENMA425. Formerly ENBE453.
Examination of the structure and function of natural biomaterials, and
cell-extracellular matrix interactions. Study physical properties of
synthetic biomaterials for biomedical applications. Understanding
molecular level interactions between biomolecules and biomaterials to
design novel biomaterials with desirable characteristics. Application
of biomaterials as implants, drug delivery systems, biosensors,
engineered materials such as artificial skin and bone growth scaffolds
will be covered.
BIOE 454 Biomaterials Laboratory (1 credits)
Prerequisite: CHEM231 and CHEM232. Corequisite: BIOE453. Recommended:
ENES220.
Hands-on experience with measurements of bulk and surface properties of
biological materials, synthesis of hydrogel, surface patterning using
soft lithography technique, and preparation of 3D agarose matrix of cell
culture. The topics cover measurements of tensile strength, hardness,
and impact strength of the biomaterials, swelling and transport behavior
of hydrogel, patterning silicon substrate using self-assembled
monolayer, and cell-biomaterials interactions in scaffold biomaterials.
BIOE 455 Basic Electronic Design (3 credits)
Prerequisite: PHYS142 or equivalent; MATH246, and BIOE241. Credit will
be granted for only one of the following: BIOE455 or ENBE455. Formerly
ENBE455.
Familiarization with basic electronic circuits and the ability to
produce simple electronic designs.
BIOE 456 Bioinstrumentation (3 credits)
Prerequisite: BIOE455; or permission of department. Credit will be
granted for only one of the following: BIOE456 or ENBE456. Formerly
ENBE456.
Study of biomedical instrumentation and biomedical equipment technology.
How biomedical equipment is used to measure information from the human
body. Hands-on experience with representative biomedical equipment.
BIOE 460 Biotechnology and Bioproduction (3 credits)
Restricted to Juniors and Seniors only. Also offered as ENES489Q. Credit
will be granted for only one of the following: BIOE460 BIOE468B, or
ENES489Q. Formerly BIOE468B.
Basics of recombinant DNA technology and biopharmaceutical
manufacturing.
BIOE 468 Selected Topics in Bioengineering (3 credits)
Prerequisite: BIOE120, BIOE121, and permission of department. Repeatable
to 9 credits if content differs.
Selected topics in Bioengineering will be covered and taught by a
variety of department faculty.
BIOE 471 Biological Systems Control (3 credits)
Two hours of lecture and two hours of laboratory per week. Prerequisite:
BIOE455; or permission of department. Credit will be granted for only
one of the following: BIOE471 or ENBE471. Formerly ENBE471.
Principles of control systems designed by biological engineers and
analysis of control mechanisms found in biological organisms. Apparent
control strategies used by biological systems will be covered.
BIOE 482 Analysis of Bioenergy Systems (3 credits)
Prerequisite: CHEM231 and ENME232; or equivalent.
Combines topics from biofuels (some of which are renewable/sustainable)
and biofuel cells. Emphasizes both engineering and biological analysis
while including a practical perspective based on specific examples from
the current literature. Ethanol from corn and sugar cane; gasoline from
biomass; use of cellulosic biomass; enzymatic and microbial biofuel
cells.
BIOE 484 Engineering in Biology (3 credits)
Prerequisite: MATH221 or MATH141; PHYS141 or PHYS161; CHEM103 or higher;
or permission of department. Recommended: BIOE454. Credit will be
granted for only one of the following: BIOE484 or ENBE484. Formerly
ENBE484.
Engineering with biological systems, with emphasis on utilization,
design, and modeling. Broad topics include differences between
biological engineering and biological science; basic sciences and how
they relate to biology; typical biological responses to environmental
stimuli; scaling, and utilization of living things.
BIOE 485 Capstone Design I: Entrepreneurship, Regulatory Issues, and Ethics (3 credits)
Prerequisite: BIOE455. Senior standing. For BIOE majors only. Credit
will be granted for only one of the following: BIOE485 or ENBE485.
Formerly ENBE485.
This is the first part of a two-semester senior capstone design course
which covers principles involved in engineering design, design
approaches, economics of design, ethics in engineering, and patent
regulations. It also helps students learn team work and write design
project proposals under the mentorship of a faculty advisor.
BIOE 486 Capstone Design II (3 credits)
Prerequisite: BIOE485 taken in the immediately preceding semester.
Senior standing. For BIOE majors only. Credit will be granted for only
one of the following: BIOE486 or ENBE486. Formerly ENBE486.
This is the second part of the senior capstone design course. This part
is independent instruction where faculty mentoring each project team
works with students to order supplies, fabricate their proposed design
under BIOE485, test the design, write the report and present it to their
fellow seniors and board of faculty mentors. Students are taught to
convert the blue print of a design to actual device and test it.
BIOE 489 Special Topics in Bioengineering (3 credits)
Repeatable to 6 credits if content differs.
Exploring a variety of topics with Bioengineering.
BIOE 601 Biomolecular and Cellular Rate Processes (3 credits)
Also offered as ENCH859B. Credit will be granted for only one of the
following: BIOE 601 or ENCH 859B.
Presentation of techniques for characterizing and manipulating
non-linear biochemical reaction networks. Advanced topics to include
mathematical modeling of the dynamics of biological systems; separation
techniques for heat sensitive biologically active materials; and rate
processes in cellular and biomolecular systems. Methods are applied to
current biotechnological systems, some include: recombinant bacteria;
plant insect and mammalian cells; and transformed cell lines.
BIOE 602 Cellular and Tissue Biomechanics (3 credits)
Introduction to the fundamentals of biomechanics including force
analysis, mechanics of deformable bodies, stress and strain, multiaxial
deformations, stress analysis, and viscoelasticity. Biomechanics of soft
and hard tissues.
BIOE 603 Electrophysiology of the Cell (3 credits)
Introduction to the electrophysiology of the cell membrane. Development
of mathematical models of different types of ionic membrane currents and
fluid compartment models, culminating in the development of functional
whole-cell models for neurons and muscle (cardiac, skeletal and smooth
muscle) cells. Characterization of volume conductor boundary value
problems encountered in electrophysiology consisting of the adequate
description of the bioelectric current source and the volume conductor
(surrounding tissue) medium.
BIOE 604 Cellular and Physiological Transport Phenomena (3 credits)
Prerequisite: BIOE332.
A study of transport processes, including momentum, energy and mass
transport, relevant to biosystems at various scales from physiological
to cellular systems. Transport leads to sets of partial differential
equations and the course revolves around approaches to solving these
equations to arrive at fundamental understanding of the physics of
transport in biosystems.
BIOE 605 Laboratory Rotations I (1 credits)
For BIOE majors only.
Provides the opportunity to experience different laboratory
environments. Students gain exposure to graduate research, learn a wide
variety of laboratory and/or computational techniques, become familiar
with Bioengineering program faculty, and develop insight on personal
research interests and direction. Laboratory rotations are required in
Fall and Spring of the first year of the Ph.D. Program. BIOE605:
Laboratory Rotations I will be held in the Fall semester. BIOE606:
Laboratory Rotations II will be held in the Spring semester.
BIOE 606 Laboratory Rotations II (1 credits)
Two hours of laboratory per week. For BIOE majors only.
Provide students with the opportunity to experience different laboratory
environments. Students gain exposure to graduate research, learn awide
variety of laboratory techniques, become familiar with BIOE faculty, and
develop insight into personal research interests and direction.
Laboratory rotations are required in the Fall and Spring of the first
year of the Ph.D. program. BIOE605: Laboratory Rotations 1 will be held
in the Fall semester; BIOE606: Laboratory Rotations 2 will be held in
the Spring semester.
BIOE 608 Bioengineering Seminar Series (1 credits)
For BIOE majors only. Repeatable to 6 credits if content differs.
A variety of topics related to Bioengineering will be presented in
weekly seminars.
BIOE 610 Instrumentation in Biological Systems (3 credits)
Prerequisite: ENBE/BIOE455 or equivalent. Credit will be granted for
only one of the following: BIOE610 or ENBE601. Formerly ENBE601.
Analyze and design electronic and computer-based instrumentation for
sensing, measurements and controls as applied to biological systems.
BIOE 611 Advanced Tissue Engineering (3 credits)
Prerequisite: At least one biology course and MATH241. Recommended:
BSCI330 and BIOE340. Credit will be granted for only one of the
following: BIOE611 or BIOE689T. Formerly BIOE689T.
A review of the fundamental principles involved in the design of
engineered tissues and organs. Both biological and engineering
fundamentals will be considered.
BIOE 645 Advanced Engineering Start Up Ventures (3 credits)
Covers principles and practices important to engineering startup
ventures, especially those involving bioengineering and medical device
enterprises, and includes the preparation of business plans and tools
used to obtain funding.
BIOE 650 Quantitative Physiology of the Cell (3 credits)
Recommended: MATH141, MATH241, MATH246 or their equivalents. Credit will
be granted for only one of the following: BIOE689Q or BIOE650. Formerly
BIOE689Q.
Introduction to quatitative aspects of neuronal, skeletal muscle, and
cardiac physiological systems, with an emphasis on cellular function
and plasticity. Complements BIOE603: Electrophysiolgy of the Cell.
BIOE 689 Special Topics in Bioengineering (1-3 credits)
For BIOE majors only. Repeatable to 06 credits if content differs.
Research Oriented Individual Instruction course.
BIOE 799 Master's Thesis Research (1-6 credits)
BIOE 898 Pre-Candidacy Research (1-8 credits)
BIOE 899 Doctoral Dissertation Research (1-8 credits)
